New hope for sickle cell: half-matched transplant without chemo
NCT ID NCT00977691
First seen May 04, 2026 · Last updated May 14, 2026 · Updated 3 times
Summary
This study tests a stem cell transplant from a half-matched family donor for adults with severe sickle cell disease or beta-thalassemia. Instead of high-dose chemotherapy, it uses low-dose radiation and immune-suppressing drugs to prepare the body. The goal is to see if this gentler approach can replace the diseased blood cells with healthy donor cells and reduce complications.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, 20892, United States
Conditions
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