One-Shot gene therapy aims to stop debilitating swelling attacks
NCT ID NCT06634420
Summary
This study is testing whether a single infusion of an experimental gene therapy called NTLA-2002 can safely and effectively reduce the number of sudden, severe swelling attacks in people with hereditary angioedema (HAE). About 60 participants will be randomly assigned to receive either the therapy or a placebo infusion. The main goal is to see if the treatment lowers the rate of HAE attacks over 28 weeks, with follow-up for nearly two years.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HEREDITARY ANGIOEDEMA are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
AARA Research Center
Dallas, Texas, 75231, United States
-
AP-HM - Hopital de la Timone
Marseille, 13385, France
-
Allergy & Asthma Clinical Research
Walnut Creek, California, 94598, United States
-
Amsterdam UMC - Locatie AMC
Amsterdam, 1105 AZ, Netherlands
-
Asthma & Allergy Associates
Colorado Springs, Colorado, 80907, United States
-
Bernstein Clinical Research Center, LLC
Cincinnati, Ohio, 45236, United States
-
CHU Grenoble-Alpes - Hopital Michallon
Grenoble, 38043, France
-
CHU de Lille - Hopital Claude Huriez
Lille, 59037, France
-
Cambridge University Hospitals NHS Foundation Trust
Cambridge, CB2 0QQ, United Kingdom
-
Campbelltown Hospital
Campbelltown, New South Wales, 2560, Australia
-
Charite Universitaetsmedizin Berlin
Berlin, 12203, Germany
-
IMMUNOe International Research Centers
Centennial, Colorado, 80112, United States
-
Icahn School of Medicine at Mount Sinai
New York, New York, 10029, United States
-
Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
-
Medical Research of Arizona
Scottsdale, Arizona, 85251, United States
-
Medizinische Hochschule Hannover (MHH)
Hanover, 30625, Germany
-
NYU Langone Health - Long Island
Mineola, New York, 11501, United States
-
New Zealand Clinical Research (NZCR)
Auckland, 1010, New Zealand
-
Ottawa Allergy Research Corporation
Ottawa, Ontario, K1H 1E4, Canada
-
Penn State Milton S. Hershey Medical Center
Hershey, Pennsylvania, 17033, United States
-
Raffi Tachdjian MD, Inc
Santa Monica, California, 90404, United States
-
Royal Melbourne Hospital
Parkville, Victoria, 3050, Australia
-
The Alfred Hospital
Melbourne, Victoria, 3004, Australia
-
Universitaetsklinikum Frankfurt - Klinikum der Johann Wolfgang Goethe Universitaet
Frankfurt, 60590, Germany
-
University of Alberta
Edmonton, Alberta, T6G 2G3, Canada
-
University of California, San Diego (UCSD)
San Diego, California, 92122, United States
-
University of Cape Town - Lung Institute - Lung Clinical Research Unit
Cape Town, 7700, South Africa
-
University of South Florida
Tampa, Florida, 33613, United States
-
Washington University in St. Louis
St Louis, Missouri, 63141, United States
Conditions
Explore the condition pages connected to this study.