Microbiome clues in early ovarian failure: study compares bacteria in women with POI and healthy controls

NCT ID NCT07275671

Completed Knowledge-focused Sponsor: Westlake University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at gut and vaginal bacteria in 20 women with premature ovarian insufficiency (POI) and 20 healthy women of similar age. POI causes ovaries to stop working normally before age 40, affecting hormones and fertility. Researchers collected stool, vaginal swabs, blood, and urine to compare the microbiome and chemical profiles. The goal was to find differences that might help understand how bacteria influence ovarian health.

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Conditions

The condition(s) this trial relates to.

primary ovarian failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PREMATURE OVARIAN INSUFFICIENCY REPRODUCTIVE HEALTH

Contacts and locations

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Locations

Shanghai Changzheng Hospital

Shanghai, China
The Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

Shanghai, China