Gut hormone GIP may calm nausea by boosting blood flow to the abdomen

NCT ID NCT07687589

First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time

Summary

This study tests whether the gut hormone GIP can reduce nausea in healthy volunteers. Nausea is triggered using other gut hormones or a medication, and GIP is given intravenously to see if it lessens the sick feeling. The goal is to better understand how the gut and brain communicate to control nausea.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Glucose-dependent Insulinotropic Polypeptide (GIP)
What this could lead to
If GIP reduces nausea, it could point toward a new treatment for nausea without strong side effects.
What could go wrong
This is a small, early study in healthy people, so results may not apply to patients with chronic nausea. The effect may be weak or absent.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Nausea Vomiting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Center for Clinical Metabolic Research, Herlev-Gentofte Hospital

    Hellerup, 2900, Denmark