New drug combo targets tough blood cancers

NCT ID NCT02935361

First seen Jan 29, 2026 · Last updated May 11, 2026 · Updated 13 times

Summary

This study tests a combination of two drugs, guadecitabine and atezolizumab, in adults with myelodysplastic syndrome or chronic myelomonocytic leukemia that has spread, returned, or not responded to prior treatment. The goal is to find the best dose and see how well the drugs work together to control the disease. About 33 participants will be enrolled in this early-phase trial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Fox Chase Cancer Center

    Philadelphia, Pennsylvania, 19111, United States

  • Temple University Hospital

    Philadelphia, Pennsylvania, 19140, United States

  • USC / Norris Comprehensive Cancer Center

    Los Angeles, California, 90033, United States

  • University of Maryland Medical Center

    Baltimore, Maryland, 21201, United States

Conditions

Explore the condition pages connected to this study.