New drug combo aims to tame advanced tumors

NCT ID NCT05840224

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 25 times

Summary

This early-phase study tests a new drug called GS-4528, given alone or with an immunotherapy drug, in adults with advanced solid tumors that have not responded to standard treatments. The main goals are to check safety and find the best dose. About 182 participants will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Asan Medical Center

    Seoul, 05505, South Korea

  • Chang Gung Memorial Hospital Linkuo Branch of the Chang Gung Medical Foundation

    Taoyuan, 333, Taiwan

  • Clinica Universidad de Navarra- Unidad Central de Ensayos Clinicos

    Pamplona, 31008, Spain

  • Hospital Universitari Vall D'Hebron- Oncology Service

    Barcelona, 08035, Spain

  • NEXT Oncology-Hospital Quironsalud Barcelona - Unidad de Ensayos Fase 1

    Barcelona, 08023, Spain

  • National Taiwan University Hospital

    Taipei, 100229, Taiwan

  • START MADRID_HM Sanchinarro-CIOCC-Unidad de Ensayos Fases I

    Madrid, 28050, Spain

  • START MADRID_Hospital Universitario Fundacion Jimenez Diaz - Unidad de Ensayos Fases I

    Madrid, 28040, Spain

  • Samsung Medical Center

    Seoul, 06351, South Korea

  • Severance Hospital, Yonsei University Health Systems

    Seoul, 06273, South Korea

  • St Bartholomew's Hospital

    London, E1 1FR, United Kingdom

  • Taichung Veterans General Hospital

    Taichung, 40705, Taiwan

  • The Ottawa Hospital

    Ottawa, K1H 8L6, Canada

  • The Royal Marsden NHS Foundation Trust

    Sutton, SM2 5PT, United Kingdom

  • The University of Washington/FHCC

    Seattle, Washington, 98109, United States

  • University Health Network, Princess Margaret Cancer Centre

    Toronto, M5G 1Z5, Canada

Conditions

Explore the condition pages connected to this study.