New hope for kids with genetic short stature: daily shot aims to boost growth

NCT ID NCT06455059

Summary

This study is testing whether a daily injection called vosoritide can safely help children with hypochondroplasia grow taller. About 80 children, aged 3 to 18, will receive either the real drug or a placebo (a dummy injection) for one year to see which group grows faster. The main goal is to see if the drug increases the children's annual growth rate compared to the placebo.

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Contacts and locations

Locations

  • Ann & Robert H. Lurie Children's Hospital of Chicago

    Chicago, Illinois, 60611, United States

  • CHU de Toulouse

    Toulouse, France

  • Centre Hospitalier Universitaire Sainte-Justine

    Montreal, Quebec, Canada

  • Children's National Medical Center

    Washington D.C., District of Columbia, 20010, United States

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS

    Rome, Italy

  • Great Ormond Street Hospital for Children NHS Foundation Trust

    London, United Kingdom

  • Hopital Necker-Enfants Malade

    Paris, France

  • Hopital de la Timone

    Marseille, France

  • Hospices Civils de Lyon - Hopital Femme Mere Enfant

    Lyon, France

  • Institute of Science Tokyo Hospital

    Tokyo, Japan

  • Instituto Giannina Gaslini

    Genoa, Italy

  • Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • Murdoch Children's Research Institute

    Parkville, Victoria, 3052, Australia

  • Nemours Alfred I. DuPont Hospital for Children

    Wilmington, Delaware, 19803, United States

  • Osaka University Hosptial

    Osaka, Japan

  • Ospedale Pediatrico Bambino Gesu

    Rome, Italy

  • SickKids - The Hospital for Sick Children

    Toronto, Ontario, Canada

  • Tokushima University Hospital

    Tokushima, Japan

  • Tottori University Hospital

    Tottori, Japan

  • Uniklinik Koln

    Cologne, Germany

  • Univeristatskinderklinik Magdeburg

    Magdeburg, Germany

  • University of Alberta Stollery Children's Hospital

    Edmonton, Alberta, Canada

  • Vithas Hospital San Jose

    Vitoria-Gasteiz, Spain

Conditions

Explore the condition pages connected to this study.