Last-Resort cell therapy targets rare cancer in single patient

NCT ID NCT06789081

First seen Jan 04, 2026 · Last updated May 16, 2026 · Updated 18 times

Summary

This study tests a made-to-order cell therapy called GCAR1 in one person with advanced alveolar soft part sarcoma that has spread and has no standard treatments left. The therapy uses the patient's own immune cells, modified to recognize and attack cancer cells that carry a protein called GPNMB. The main goal is to see if the tumor shrinks or disappears on scans taken 4 to 6 weeks after treatment.

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Contacts and locations

Locations

  • Arthur J.E. Child Comprehensive Cancer Centre

    Calgary, Alberta, T2N 5G2, Canada

Conditions

Explore the condition pages connected to this study.