Fluid strategy during surgery may change airway size, study finds
NCT ID NCT07477392
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 145 adults having spine surgery lasting over 2 hours. Researchers compared standard fluid therapy (based on weight and vital signs) with goal-directed therapy (using a heart monitor to guide fluids). They measured tongue and epiglottis thickness with ultrasound to see if the fluid method made a difference. The goal was to understand how fluid management affects airway swelling, not to treat a disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Goal-directed fluid therapy (intravenous fluids guided by pulse pressure variation)
- What this could lead to
- If successful, this could help doctors choose the best fluid strategy to reduce airway swelling after long surgeries.
- What could go wrong
- This is a small, completed study focused on measurements, not a treatment. Results may not change practice or apply to other surgeries.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Izmir Bozyaka Training and Research Hospital
Izmir, Bozyaka, 35100, Turkey (Türkiye)
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