Brain cleanse trial: can sleep or nerve stimulation clear toxic proteins?
NCT ID NCT06421532
First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 30 times
Summary
This study tests whether a sleep-deepening drug (lower-sodium oxybate) or a nerve stimulation device (non-invasive vagus nerve stimulation), or both, can help the brain clear amyloid-beta proteins in people with cerebral amyloid angiopathy (CAA). About 60 adults with CAA will receive one or both treatments for a short period. Researchers will measure protein levels in spinal fluid and use advanced MRI scans to track brain changes.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CEREBRAL AMYLOID ANGIOPATHY are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Leiden University Medical Center (LUMC)
Leiden, 2333ZA, Netherlands
Conditions
Explore the condition pages connected to this study.