Why are people with this rare bone disorder prone to diabetes?

NCT ID NCT03761290

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This pilot study aims to understand why people with pseudohypoparathyroidism type 1A (PHP1A) have a higher risk of type 2 diabetes. Researchers will measure insulin sensitivity and beta-cell function in 14 participants with PHP1A or related conditions, comparing them to matched healthy controls. The study was terminated early, so results may be limited.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If successful, this study could reveal why type 2 diabetes is more common in people with PHP1A, pointing toward future prevention or treatment strategies.
What could go wrong
This is a small, terminated pilot study with only 14 participants, so results may be limited and not generalizable. No direct treatment is being tested.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ALBRIGHT HEREDITARY OSTEODYSTROPHY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37212, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.