Why are people with this rare bone disorder prone to diabetes?
NCT ID NCT03761290
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This pilot study aims to understand why people with pseudohypoparathyroidism type 1A (PHP1A) have a higher risk of type 2 diabetes. Researchers will measure insulin sensitivity and beta-cell function in 14 participants with PHP1A or related conditions, comparing them to matched healthy controls. The study was terminated early, so results may be limited.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- What this could lead to
- If successful, this study could reveal why type 2 diabetes is more common in people with PHP1A, pointing toward future prevention or treatment strategies.
- What could go wrong
- This is a small, terminated pilot study with only 14 participants, so results may be limited and not generalizable. No direct treatment is being tested.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Vanderbilt University Medical Center
Nashville, Tennessee, 37212, United States
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