Can steroids rescue livers damaged by medications?

NCT ID NCT06922669

Recruiting now Disease control Sponsor: General Hospital of Shenyang Military Region Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a steroid drug (methylprednisolone) can help people with severe liver injury caused by medications. The trial includes 232 adults with high bilirubin levels. Participants receive either steroids plus standard care or standard care alone, and doctors track liver recovery over weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Methylprednisolone (a steroid drug)
What this could lead to: If it works, this could provide a standard treatment for severe drug-induced liver injury with high bilirubin, potentially preventing liver failure.
What could go wrong: This is a mid-stage trial with 232 participants, so results may not apply to everyone. Steroids have side effects like infection risk and may not help all patients.

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Conditions

The condition(s) this trial relates to.

drug-induced liver injury hyperbilirubinemia liver failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DRUG INDUCED LIVER INJURY

Contacts and locations

Locations

Department of Gastroenterology, General Hospital of Northern Theater Command (formerly called General Hospital of Shenyang Military Area)
RECRUITING

Shenyang, Liaoning, 110840, China

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