Steroid shock: rapid stop may be as safe as slow taper

NCT ID NCT03153527

First seen Feb 28, 2026 · Last updated May 16, 2026 · Updated 9 times

Summary

This study compares two ways to stop long-term steroid treatment in adults with inflammatory or autoimmune diseases. One group stops immediately, while the other tapers down over 4 weeks. The goal is to see if rapid stopping is as safe and does not increase the risk of adrenal crisis, hospitalization, or death. About 530 participants will be followed to track these outcomes.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Center for Primary Health Care,University of Basel, Kantonsspital Baselland

    TERMINATED

    Liestal, 4410, Switzerland

  • Departement of Internal Medicine, Kantonsspital Aarau

    RECRUITING

    Aarau, 5001, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Department of Internal Medicine, Kantonsspital Münsterlingen

    RECRUITING

    Münsterlingen, 8596, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Department of Internal Medicine, Kantonsspital St. Gallen

    RECRUITING

    Sankt Gallen, 9007, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Department of Rheumatology, Immunology, and Allergology, Inselspital

    TERMINATED

    Bern, 3010, Switzerland

  • Dept. of Endocrinology, Diabetology and Clinical Nutrition, University Hospital

    TERMINATED

    Zurich, 8091, Switzerland

  • Division of Gastroenterology, Spital Bülach AG

    TERMINATED

    Bülach, 8180, Switzerland

  • Endocrinology/Diabetology/Metabolism; University Hospital Basel

    TERMINATED

    Basel, 4031, Switzerland

  • Geneva University Hospitals

    RECRUITING

    Geneva, 1205, Switzerland

    Contact Phone: •••-•••-••••

    Contact

  • Internal Medicine, Kantonsspital Baselland/Liestal

    RECRUITING

    Liestal, 4410, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kantonsspital Baden

    RECRUITING

    Baden, 5404, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kantonsspital Frauenfeld

    RECRUITING

    Frauenfeld, 8501, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • St. Claraspital Basel

    RECRUITING

    Basel, 4058, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Stoffwechselzentrum, Kantonsspital Olten

    TERMINATED

    Olten, 4600, Switzerland

  • University Hospital Frankfurt

    RECRUITING

    Frankfurt, Germany

    Contact

    Contact

    Contact

  • University Hospital Würzburg

    RECRUITING

    Würzburg, 97080, Germany

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.