Experimental cell therapy GLPG5101 shows promise for Hard-to-Treat lymphoma

NCT ID NCT06561425

First seen Nov 01, 2025 · Last updated May 02, 2026 · Updated 25 times

Summary

This study tests an experimental treatment called GLPG5101 for people with B-cell non-Hodgkin lymphoma that has come back or not responded to standard therapy. The treatment is made from the patient's own immune cells and given as a one-time infusion. The study has two phases: the first finds the best dose with the fewest side effects, and the second checks how well that dose works. About 130 participants will take part across multiple centers.

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Contacts and locations

Locations

  • Academisch Medisch Centrum

    Amsterdam, 1105 AZ, Netherlands

  • Antwerp University Hospital

    Edegem, 2650, Belgium

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • CHU De Liège

    Liège, 4000, Belgium

  • Cliniques Universitaires Saint-Luc

    Woluwe-Saint-Lambert, 1200, Belgium

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

    Rotterdam, 3015 GD, Netherlands

  • Leiden University Medical Center

    Leiden, 2333 ZA, Netherlands

  • Tufts Medical Center

    Boston, Massachusetts, 02111, United States

  • UZ Leuven

    Leuven, 3000, Belgium

Conditions

Explore the condition pages connected to this study.