New hope for lymphoma patients Who've run out of options

NCT ID NCT06084936

Recruiting now Disease control Sponsor: Hoffmann-La Roche Source: ClinicalTrials.gov ↗

First seen Sep 30, 2025 · Last updated Apr 20, 2026 · Updated 28 times

Summary

This study is testing whether a new drug called glofitamab works better than current standard treatments for people with mantle cell lymphoma that has returned or stopped responding to previous therapies. About 182 participants will receive either glofitamab alone or one of two standard combination treatments chosen by their doctor. The main goal is to see which approach keeps the cancer from growing longer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

A.O. Città della Salute e della Scienza D - Osp. S. Giov. Battista Molinette
RECRUITING

Turin, Piedmont, 10126, Italy
Akademiska sjukhuset, Onkologkliniken
RECRUITING

Uppsala, 751 85, Sweden
Alta Bates Summit Medical Center
WITHDRAWN

Berkeley, California, 94704, United States
Americas Medical City
RECRUITING

Rio de Janeiro, 22775-001, Brazil
Asan Medical Center
ACTIVE_NOT_RECRUITING

Seoul, 05505, South Korea
Auxilio Mutuo Cancer Center
RECRUITING

San Juan, 00918, Puerto Rico
Avera Cancer Institute
WITHDRAWN

Sioux Falls, South Dakota, 57105, United States
Beijing Tong Ren Hospital, Capital Medical University
RECRUITING

Beijing, 100730, China
Beneficencia Portuguesa de Sao Paulo
RECRUITING

São Paulo, 01321-00, Brazil
CHU NANTES - Hôtel Dieu
RECRUITING

Nantes, 44093, France
Calvary Mater Newcastle
RECRUITING

Waratah, New South Wales, 2298, Australia
Chang Gung Medical Foundation - Linkou
RECRUITING

Taoyuan District, 333, Taiwan
Chongqing Cancer Hospital
RECRUITING

Chongqing, 400030, China
Christie Hospital Nhs Trust
RECRUITING

Manchester, M2O 4BX, United Kingdom
Chungnam National University Hospital
WITHDRAWN

Daejeon, 35015, South Korea
City of Hope Cancer Center
RECRUITING

Duarte, California, 91010, United States
Complejo Hospitalario Universitario A Coruña (CHUAC)
RECRUITING

A Coruña, 15006, Spain
Derriford Hospital
RECRUITING

Plymouth, PL6 8DH, United Kingdom
Epworth Hospital
RECRUITING

Richmond, Victoria, 3121, Australia
Fudan University Shanghai Cancer Center
ACTIVE_NOT_RECRUITING

Shanghai, 200032, China
Fujian Provincial Cancer Hospital
RECRUITING

Fuzhou, 350014, China
Georgetown University
RECRUITING

Washington D.C., District of Columbia, 20007, United States
Guangxi Cancer Hospital of Guangxi Medical University
RECRUITING

Nanning, 530021, China
Henan Cancer Hospital
RECRUITING

Zhengzhou, 450008, China
Hopital Claude Huriez
RECRUITING

Lille, 59037, France
Hopital Necker
RECRUITING

Paris, 75743, France
Hopital Saint Eloi
RECRUITING

Montpellier, 34295, France
Hospital A. C. Camargo
RECRUITING

São Paulo, São Paulo, 01509-010, Brazil
Hospital Alemao Oswaldo Cruz
RECRUITING

São Paulo, São Paulo, 01327-001, Brazil
Hospital Clinic de Barcelona
RECRUITING

Barcelona, 08036, Spain
Hospital General Universitario J.M Morales Meseguer
RECRUITING

Murcia, 30008, Spain
Hospital Mae de Deus
RECRUITING

Porto Alegre, Rio Grande do Sul, 90110-000, Brazil
Hospital Paulistano
RECRUITING

São Paulo, São Paulo, 01321-000, Brazil
Hospital Sao Rafael - HSR
WITHDRAWN

Salvador, Estado de Bahia, 41253-190, Brazil
Hospital Universitari Vall d'Hebron
RECRUITING

Barcelona, 08035, Spain
Hospital Universitario Puerta del Mar
RECRUITING

Cadiz, Cadiz, 11009, Spain
Humanitas Gavazzeni
RECRUITING

Bergamo, Lombardy, 24121, Italy
ICTR Curitiba
RECRUITING

Curitiba, Paraná, 80510-130, Brazil
INSTITUT CURIE_SITE PARIS - Service d'Oncologie Médicale.
RECRUITING

Paris, 75005, France
Indiana University
WITHDRAWN

Indianapolis, Indiana, 46202, United States
Instituto D'Or Pesquisa e Ensino
RECRUITING

São Paulo, São Paulo, 04502-001, Brazil
Irccs Istituto Europeo Di Oncologia (IEO)
RECRUITING

Milan, Lombardy, 20141, Italy
Lincolnshire County Hospital
RECRUITING

Lincoln, LN2 5QY, United Kingdom
Medical University of S. Carolina
WITHDRAWN

Charleston, South Carolina, 29425, United States
NHS Greater Glasgow and Clyde
RECRUITING

Glasgow, G12 0YN, United Kingdom
National Taiwan Universtiy Hospital
RECRUITING

Taipei, 100, Taiwan
Oxford Churchill Hospital
RECRUITING

Oxford, OX3 7LE, United Kingdom
Policlinico S.Orsola-Malpighi
RECRUITING

Bologna, Emilia-Romagna, 40138, Italy
Princess Margaret Cancer Center
RECRUITING

Toronto, Ontario, M5G 2M9, Canada
Renovatio Clinical
RECRUITING

The Woodlands, Texas, 77380, United States
Renovatio Clinical - El Paso
RECRUITING

El Paso, Texas, 79915, United States
Royal Adelaide Hospital
RECRUITING

Adelaide, South Australia, 5000, Australia
Rutgers Cancer Institute of New Jersey
RECRUITING

New Brunswick, New Jersey, 08901, United States
SC Ematologia, AO SS. Antonio e Biagio e C. Arrigo
RECRUITING

Alessandria, Piedmont, 15121, Italy
Samsung Medical Center
ACTIVE_NOT_RECRUITING

Seoul, 135-710, South Korea
Seoul National University Hospital
ACTIVE_NOT_RECRUITING

Seoul, 03080, South Korea
Severance Hospital, Yonsei University Health System
ACTIVE_NOT_RECRUITING

Seoul, 003-722, South Korea
Skånes University Hospital, Skånes Department of Onclology
RECRUITING

Lund, 221 85, Sweden
St. Luke's Hospital
RECRUITING

Chesterfield, Missouri, 63017, United States
Sun yat-sen University Cancer Center
ACTIVE_NOT_RECRUITING

Guangzhou, 510060, China
The First Affiliated Hospital of China Medical University
RECRUITING

Shenyang, 110001, China
The First Affiliated Hospital of Wenzhou Medical University
COMPLETED

Wenzhou, 325035, China
The First Affiliated Hospital of Zhengzhou University
RECRUITING

Zhengzhou, 450003, China
The First Hospital of Jilin University
RECRUITING

Changchun, 130021, China
The Ottawa Hospital - General Campus
RECRUITING

Ottawa, Ontario, K1H 8L6, Canada
University College London Hospital
RECRUITING

London, NW1 2PG, United Kingdom
University of California Los Angeles (UCLA) - Cancer Care - Santa Monica
RECRUITING

Santa Monica, California, 90404-2023, United States
University of Miami
RECRUITING

Coral Gables, Florida, 33146, United States
University of Michigan Health System
RECRUITING

Ann Arbor, Michigan, 48109, United States
University of Rochester
RECRUITING

Rochester, New York, 14642, United States
University of Virginia
RECRUITING

Charlottesville, Virginia, 22906, United States
Victoria Hospital - London Health Sciences Centre
RECRUITING

London, Ontario, N6A 5W9, Canada
West China Hospital of Sichuan University
ACTIVE_NOT_RECRUITING

Chengdu, 610041, China
West Virginia University
RECRUITING

Morgantown, West Virginia, 26506, United States
Yale Cancer Center
RECRUITING

New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.

LYMPHOMA