New hope when CAR-T fails: experimental drug targets stubborn lymphoma

NCT ID NCT04703686

Summary

This study tested an experimental drug called glofitamab for patients with aggressive lymphomas whose cancer returned or didn't respond after CAR-T cell therapy. The trial enrolled 67 patients across two groups with different lymphoma types. Researchers aimed to see if this new antibody treatment could control the cancer and extend survival for these difficult-to-treat cases.

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Contacts and locations

Locations

  • APHP - Hôpital Saint Antoine

    Paris, France

  • APHP - Hôpital de la Pitiè Salpetrière

    Paris, France

  • CHRU Lille - Hôpital Claude Huriez

    Lille, 59037, France

  • CHU Amiens Picardie Site sud

    Amiens, France

  • CHU Lyon Sud

    Pierre-Bénite, 69130, France

  • CHU Montpellier

    Montpellier, 34295, France

  • CHU Nantes

    Nantes, 44093, France

  • CHU Tours Hopital Bretonneau

    Tours, 37044, France

  • CHU de Bordeaux - Hôpital Haut Leveque

    Pessac, 33604, France

  • CHU de Brabois

    Vandœuvre-lès-Nancy, France

  • CHU de Clermont Ferrand

    Clermont-Ferrand, 63000, France

  • CHU de Dijon - Hôpital le Bocage

    Dijon, 21034, France

  • CHU de Grenoble

    Grenoble, 38043, France

  • CHU de Rennes - Hôpital Pontchaillou

    Rennes, 35033, France

  • Centre Henri Becquerel

    Rouen, 76038, France

  • Hopital Henri Mondor

    Créteil, 94010, France

  • Hopital Necker enfants malades

    Paris, 7574, France

  • Hôpital Saint Louis

    Paris, 75475, France

  • IUCT Oncopole

    Toulouse, 31059, France

Conditions

Explore the condition pages connected to this study.