New immunotherapy cocktail aims to tackle lymphoma without chemo

NCT ID NCT05783596

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 24 times

Summary

This study tests whether combining two immunotherapy drugs, glofitamab and obinutuzumab, can safely and effectively treat people newly diagnosed with follicular lymphoma or marginal zone lymphoma. About 47 participants who have not had prior treatment will receive the drug combination. The goal is to see how many achieve a complete metabolic response (cancer disappearance on scans) by the end of treatment.

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Columbia University Irving Medical Center

    New York, New York, 10032, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Mount Sinai Medical Center

    New York, New York, 10128, United States

Conditions

Explore the condition pages connected to this study.