New hope for Tough-to-Treat lymphoma: experimental combo aims to shrink tumors fast
NCT ID NCT05364424
Summary
This study tested a new combination of drugs for people with an aggressive type of lymphoma (DLBCL) that had come back or stopped responding to their first treatment. The goal was to see if adding a new drug called glofitamab to a standard chemotherapy regimen could effectively shrink tumors and control the disease, making patients eligible for a follow-up stem cell transplant or CAR-T therapy. Researchers measured how well and safely the combination worked in 43 participants.
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Contacts and locations
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Locations
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Chao Family Comprehensive Cancer Center UCI
Orange, California, 92868, United States
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Cleveland Clinic Foundation
Cleveland, Ohio, 44195, United States
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MD Anderson Cancer Center
Houston, Texas, 77030, United States
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Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Memorial Cancer Institute at Memorial West
Pembroke Pines, Florida, 33028, United States
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New York University Langone Medical Center
New York, New York, 10016, United States
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The University of Chicago
Chicago, Illinois, 60637, United States
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Tulane Medical Center
New Orleans, Louisiana, 70112, United States
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UMASS Memorial Medical Center
Worcester, Massachusetts, 01655, United States
Conditions
Explore the condition pages connected to this study.