New drug shows promise for rare childhood disorder

NCT ID NCT05549219

First seen Jan 07, 2026 · Last updated Apr 24, 2026 · Updated 22 times

Summary

This study tested an experimental drug called GLM101 in 27 people with PMM2-CDG, a rare genetic condition that affects movement and development. Participants received different doses of the drug intravenously over 24 weeks. The main goal was to see if the drug improves coordination and to check its safety.

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Contacts and locations

Locations

  • Clinical Research of West Florida

    Tampa, Florida, 33606, United States

  • Great Ormond Street Hospital

    London, WC1N3JH, United Kingdom

  • Hospital Sant Joan de Déu

    Barcelona, 08950, Spain

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

Conditions

Explore the condition pages connected to this study.