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New drug trial aims to better control dangerous blood disorder

NCT ID NCT06093672

Recruiting now Disease control Sponsor: Italfarmaco Source: ClinicalTrials.gov ↗

Summary

This study is testing if an investigational drug called Givinostat works better than the current standard treatment, hydroxyurea, for adults with a high-risk form of a blood cancer called polycythemia vera. The goal is to see if Givinostat can more effectively control blood counts, reduce symptoms, and lower the long-term risks of blood clots and disease progression. About 220 patients will be randomly assigned to receive one of the two treatments for 48 weeks.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • A.O.U. Maggiore della Carità

    RECRUITING

    Novara, Piedmont, 28100, Italy

  • Acibadem City Clinic Multiprofile Hospital for Active Treatment Tokuda

    RECRUITING

    Sofia, Sofia-Grad, 1407, Bulgaria

  • Albert Schweitzer Ziekenhuis

    NOT_YET_RECRUITING

    Dordrecht, South Holland, 3318 AT, Netherlands

  • American Oncology Partners of Maryland, PA

    RECRUITING

    Bethesda, Maryland, 20852, United States

    Contact

  • Assuta Medical Center

    RECRUITING

    Tel Aviv, Tel Aviv, 60000, Israel

  • Azienda Ospedaliera Città della Salute e della Scienza di Torino

    RECRUITING

    Turin, Piedmont, 10126, Italy

  • Azienda Ospedaliera Papa Giovanni XXIII

    RECRUITING

    Bergamo, Lombardy, 24127, Italy

  • Azienda Ospedaliera Universitaria Careggi

    RECRUITING

    Florence, Tuscany, 50134, Italy

  • Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone

    RECRUITING

    Palermo, Sicily, 90127, Italy

  • Azienda Ospedaliero Universitaria Policlinico G Rodolico San Marco di Catania

    NOT_YET_RECRUITING

    Catania, Sicily, 95123, Italy

  • Azienda Ospedaliero Universitaria delle Marche

    RECRUITING

    Ancona, The Marches, 60126, Italy

  • Azienda Ospedaliero-Universitaria Di Bologna IRCCS Istituto Di Ricerca E Di Cura A Carattere Scientifico

    RECRUITING

    Bologna, Emilia-Romagna, 40138, Italy

  • Azienda Sanitaria Ospedaliera S. Croce e Carle

    RECRUITING

    Cuneo, Piedmont, 12100, Italy

  • Azienda Sanitaria Universitaria Friuli Centrale

    RECRUITING

    Udine, Friuli Venezia Giulia, 33100, Italy

  • Azienda USL IRCCS di Reggio Emilia

    RECRUITING

    Reggio Emilia, Emilia-Romagna, 42123, Italy

  • Belfast City Hospital

    NOT_YET_RECRUITING

    Belfast, BT9 7AB, United Kingdom

  • Bnai Zion Medical Center

    TERMINATED

    Haifa, 31048, Israel

  • CHU Amiens Hôpital Sud

    RECRUITING

    Amiens, Somme, 80054, France

  • CHU Angers

    RECRUITING

    Angers, Maine-et-Loire, 49000, France

  • CHU Nantes

    RECRUITING

    Nantes, Loire-Atlantique, 44000, France

  • CHU de Nice

    RECRUITING

    Nice, Alpes-Maritimes, 6202, France

  • Carmel Medical Center

    TERMINATED

    Haifa, 34362, Israel

  • Centre Hospitalier de Saint-Quentin

    RECRUITING

    Saint-Quentin, Aisne, 2100, France

  • Centre Hospitalier de Troyes

    RECRUITING

    Troyes, Aube, 10000, France

  • Clinical Center of Vojvodina

    RECRUITING

    Novi Sad, 21000, Serbia

  • Clinical Hospital Center Bezanijska Kosa

    RECRUITING

    Belgrade, 11000, Serbia

  • Clinical Hospital Center Rijeka

    NOT_YET_RECRUITING

    Rijeka, 51000, Croatia

  • Clinical Hospital Center Rijeka - PPDS

    RECRUITING

    Rijeka, 51000, Croatia

  • Clinical Hospital Center Zemun

    RECRUITING

    Belgrade, 11000, Serbia

  • Clinical Hospital Dubrava

    RECRUITING

    Zagreb, City of Zagreb, 10000, Croatia

  • Connolly Hospital Blanchardstown

    NOT_YET_RECRUITING

    Dublin, 15, Ireland

  • Cork University Hospital

    RECRUITING

    Cork, Ireland

  • Emad Ibrahim, MD, Inc

    RECRUITING

    Redlands, California, 92373, United States

  • Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico

    RECRUITING

    Milan, Lombardy, 20122, Italy

  • Fondazione Policlinico Universitario Campus Bio-Medico di Roma

    RECRUITING

    Rome, Lazio, 00128, Italy

  • Gemeinschaftspraxis Hämatologie - Onkologie

    RECRUITING

    Dresden, Saxony, 01307, Germany

  • General Hospital Sibenik

    NOT_YET_RECRUITING

    Šibenik, 22000, Croatia

  • Grande Ospedale Metropolitano Bianchi-Melacrino-Morelli

    RECRUITING

    Reggio Calabria, Calabria, 89133, Italy

  • Gyor-Moson-Sopron Vármegyei Petz Aladár Egyetemi Oktató Kórház

    RECRUITING

    Győr, Győr-Moson-Sopron, 9024, Hungary

  • Hadassah Medical Center - PPDS

    TERMINATED

    Jerusalem, Jerusalem, 91120, Israel

  • Hopital d'Argenteuil

    NOT_YET_RECRUITING

    Argenteuil, Île-de-France Region, 95107, France

  • Hospital General Universitario Dr. Balmis

    RECRUITING

    Alicante, 3010, Spain

  • Hospital Universitari i Politecnic La Fe de Valencia

    RECRUITING

    Valencia, 46026, Spain

  • Hospital Universitario Ramon y Cajal

    RECRUITING

    Madrid, 28034, Spain

  • Hospital Universitario Virgen de la Victoria

    RECRUITING

    Málaga, 29010, Spain

  • Hôpital Bretonneau

    RECRUITING

    Tours, Indre-et-Loire, 37044, France

  • Hôpital Saint Louis

    RECRUITING

    Paris, 75010, France

  • ICO Badalona-H.U. Germans Trias i Pujol

    NOT_YET_RECRUITING

    Badalona, Barcelona, 8916, Spain

  • Icahn School of Medicine at Mount Sinai

    RECRUITING

    New York, New York, 10029, United States

  • Imperial College Healthcare NHS Trust

    RECRUITING

    London, W12 0HS, United Kingdom

  • Indywidualna Specjalistyczna Praktyka Lekarska Tomasz Woźny

    RECRUITING

    Poznan, 60-549, Poland

  • Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST S.r.l

    RECRUITING

    Meldola, Emilia-Romagna, 47014, Italy

  • Istituto Tumori "Giovanni Paolo II" I.R.C.C.S.

    RECRUITING

    Bari, Apulia, 70124, Italy

  • Klinikum Wels-Grieskirchen GmbH

    RECRUITING

    Wels, Upper Austria, 4600, Austria

  • Landesklinikum Wiener Neustadt

    RECRUITING

    Wiener Neustadt, Lower Austria, 2700, Austria

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

  • Mater Misericordiae University Hospital

    RECRUITING

    Dublin, 7, Ireland

  • Medisch Spectrum Twente

    NOT_YET_RECRUITING

    Enschede, Overijssel, 7512 KZ, Netherlands

  • Medizinische Fakultät Mannheim der Universität Heidelberg, Universitätsmedizin Mannheim

    RECRUITING

    Mannheim, Baden-Wurttemberg, 68167, Germany

  • Medizinische Universitat Wien (Medical University of Vienna)

    RECRUITING

    Vienna, Vienna, 1090, Austria

  • OncoResearch Lerchenfeld GmbH

    RECRUITING

    Hamburg, 22081, Germany

  • Oncology Associates of Oregon, P.C.

    RECRUITING

    Eugene, Oregon, 97401, United States

  • Ordensklinikum Linz GmbH Elisabethinen

    RECRUITING

    Linz, Upper Austria, 4020, Austria

  • Spaarne Gasthuis

    NOT_YET_RECRUITING

    Hoofddorp, North Holland, 2134 TM, Netherlands

  • Specjalistyczny Szpital im. dra Alfreda Sokołowskiego

    RECRUITING

    Wałbrzych, 58-309, Poland

  • Szabolcs-Szatmár-Bereg Vármegyei Oktatókórház

    RECRUITING

    Nyíregyháza, Szabolcs-Szatmár-Bereg, 4400, Hungary

  • Texas Oncology (Webster) - USOR

    RECRUITING

    Houston, Texas, 77089, United States

  • Texas Oncology-Denison Cancer Center

    RECRUITING

    Sherman, Texas, 75090, United States

    Contact

  • The Cleveland Clinic Foundation

    RECRUITING

    Cleveland, Ohio, 44195, United States

  • The James Cancer Hospital and Solove Research Institute

    RECRUITING

    Roanoke, Virginia, 43210, United States

  • Tolna Vármegyei Megyei Balassa János Kórház

    RECRUITING

    Szekszárd, Tolna County, 7100, Hungary

  • US Oncology Inc

    RECRUITING

    Englewood, Colorado, 80113, United States

  • University Clinical Center Nis

    RECRUITING

    Niš, 18000, Serbia

  • University Clinical Center of Serbia

    RECRUITING

    Belgrade, 11000, Serbia

  • University Multiprofile Hospital for Active Treatment - Prof. Dr. Stoyan Kirkovich AD

    RECRUITING

    Stara Zagora, 6003, Bulgaria

  • University Multiprofile Hospital for Active Treatment Sveti Georgi EAD

    RECRUITING

    Plovdiv, 4001, Bulgaria

  • University of Alabama at Birmingham

    NOT_YET_RECRUITING

    Birmingham, Alabama, 35294-0001, United States

  • University of North Carolina at Chapel Hill

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

  • University of Utah - Huntsman Cancer Institute - PPDS

    RECRUITING

    Salt Lake City, Utah, 84112, United States

  • Universitätsmedizin Halle, Universitätsklinikum Halle, Klinik für Innere Medizin IV

    RECRUITING

    Halle, Saxony-Anhalt, 06120, Germany

  • Uniwersytecki Szpital Kliniczny im. Jana Mikulicza- Radeckiego we Wrocławiu

    NOT_YET_RECRUITING

    Wroclaw, 50-367, Poland

  • VA Puget Sound Health Care System - NAVREF - PPDS

    RECRUITING

    Seattle, Washington, 98108-1532, United States

Conditions

Explore the condition pages connected to this study.

POLYCYTHEMIA VERA