Can glutathione boost gum lightening? a Split-Mouth trial investigates
NCT ID NCT07748507
First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time
Summary
This trial tests whether adding a glutathione gel to microneedling improves the lightening of dark gums compared to microneedling alone. Fifteen healthy adults with gum pigmentation will receive both treatments on different sides of their mouth to compare results. The study measures changes in pigmentation and any pain or discomfort, aiming to find a better cosmetic option for smile aesthetics.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Microneedling with and without 0.5% glutathione gel
- What this could lead to
- If successful, this could offer a more effective and less invasive option for reducing gum pigmentation, improving smile aesthetics.
- What could go wrong
- This is a small, early-stage trial with only 15 participants, so results may not apply broadly. The procedure may cause discomfort, and repigmentation could occur over time.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for GINGIIVAL HYPERPIGMENTATION are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
krishnadevaraya college of dental sciences and Hospital
Bangalore, Kranataka, 562157, India