New hope for transplant patients: experimental drug targets severe GVHD

NCT ID NCT07197112

First seen Oct 31, 2025 · Last updated May 05, 2026 · Updated 23 times

Summary

This study tests an experimental drug called gimacabtinib in people who have acute graft-versus-host disease (GVHD) after a stem cell transplant and whose condition did not improve with standard second-line therapy. The goal is to see if the drug can control the disease and improve survival. About 15 adults will take the drug by mouth, and doctors will check their response after 28 days.

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