Repurposed leukemia drug tested for Tough-to-Treat lung cancer

NCT ID NCT07140016

Summary

This early-phase study is testing the safety and tolerability of gilteritinib, a drug already approved for a type of leukemia, in adults with advanced ALK-positive non-small cell lung cancer (NSCLC) whose cancer has stopped responding to prior ALK inhibitor treatments. About 40 participants will take gilteritinib tablets daily in 28-day cycles, starting at a lower dose that may increase if tolerated. The main goal is to understand the side effects and determine safe dosing for this new use of the medication.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hackensack University Medical Center

    RECRUITING

    Hackensack, New Jersey, 07601, United States

  • OSF Health Care

    RECRUITING

    Peoria, Illinois, 61637, United States

  • Site ES34006

    RECRUITING

    Madrid, Spain

  • Site ES34008

    RECRUITING

    Málaga, Spain

  • Site ES34011

    RECRUITING

    Madrid, Spain

  • University of Michigan Health Systems

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

  • Virginia Cancer Specialists PC

    RECRUITING

    Fairfax, Virginia, 22031, United States

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.