New drug duo targets Hard-to-Treat cancers in phase 2 trial

NCT ID NCT07318649

First seen Jan 09, 2026 · Last updated May 15, 2026 · Updated 17 times

Summary

This study tests a combination of two experimental drugs (GH21 and D-1553) in 120 adults with advanced solid tumors that have a specific genetic change called KRASG12C. Participants must have already tried standard treatments or have no standard options, and have previously taken a KRASG12C inhibitor. The goal is to see if the combination shrinks tumors and is safe, with treatment continuing as long as it helps and side effects are manageable.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Zhejiang Cancer Hospital

    Hangzhou, Zhejiang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.