Natural annatto compound tested for statin muscle aches
NCT ID NCT05312424
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether a supplement called geranylgeraniol (GG), derived from annatto seeds, can reduce muscle pain and weakness caused by statin medications. Researchers will give 95 adults either a low or high dose of GG or a placebo for three months. The goal is to see if GG improves muscle symptoms and strength without interfering with statin benefits.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- geranylgeraniol (GG) from annatto
- What this could lead to
- If it works, this could offer a natural way to reduce muscle pain and weakness in people who need statins for heart health.
- What could go wrong
- This is an early Phase 1/2 trial with only 95 people, so results may not apply to everyone. The supplement might not work better than placebo, and side effects are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Texas Tech University Health Sciences Center
RECRUITINGLubbock, Texas, 79430, United States