Natural annatto compound tested for statin muscle aches
NCT ID NCT05312424
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether a supplement called geranylgeraniol (GG), derived from annatto seeds, can reduce muscle pain and weakness caused by statin medications. Researchers will give 95 adults either a low or high dose of GG or a placebo for three months. The goal is to see if GG improves muscle symptoms and strength without interfering with statin benefits.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
geranylgeraniol (GG) from annatto
What this could lead to
If it works, this could offer a natural way to reduce muscle pain and weakness in people who need statins for heart health.
What could go wrong
This is an early Phase 1/2 trial with only 95 people, so results may not apply to everyone. The supplement might not work better than placebo, and side effects are possible.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Texas Tech University Health Sciences Center
RECRUITINGLubbock, Texas, 79430, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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