New drug targets 'Undruggable' cancer mutation in major trial

NCT ID NCT05005234

Summary

This clinical trial tested a new oral drug called GFH925 for people with advanced solid tumors that have a specific genetic change called KRAS G12C. The study aimed to find a safe dose and see if the drug could shrink tumors in cancers like non-small cell lung cancer and colorectal cancer. It involved 334 adult participants whose cancer had progressed despite prior treatments.

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Contacts and locations

Locations

  • Guangdong Provincial People's Hospital

    Guangzhou, Guangdong, 510000, China

Conditions

Explore the condition pages connected to this study.