New pill targets Hard-to-Treat cancers in 334-Patient trial

NCT ID NCT05005234

First seen Nov 17, 2025 · Last updated May 13, 2026 · Updated 23 times

Summary

This study tested a drug called GFH925 in 334 people with advanced solid tumors that have a specific genetic change called KRAS G12C. The goal was to check the drug's safety, find the right dose, and see if it shrinks tumors in cancers like lung and colorectal cancer. Participants took the drug by mouth, and researchers monitored side effects and tumor response.

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Contacts and locations

Locations

  • Guangdong Provincial People's Hospital

    Guangzhou, Guangdong, 510000, China

Conditions

Explore the condition pages connected to this study.