Can a new pill beat acid reflux? two drugs go Head-to-Head
NCT ID NCT07727629
First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time
Summary
This phase 1 trial tests two experimental oral drugs, UI059 and UIC202201, in healthy adult volunteers to see how safe they are and how well they control stomach acid. Each participant takes one drug daily for a week, then switches to the other after a break. The goal is to compare their effects on acid levels in the stomach and find out which one might work better for treating GERD.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- two experimental oral drugs for GERD, UI059 and UIC202201
- What this could lead to
- If one drug proves safer or more effective at controlling stomach acid, it could become a new treatment option for GERD.
- What could go wrong
- This is an early phase 1 trial in healthy volunteers, not patients with GERD. The drugs may not work as expected or could have side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for GASTRO ESOPHAGEAL REFLUX DISORDER are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Chungbuk national university hospital
Cheongju-si, North Chungcheong, 28644, South Korea