Gene study aims to unlock why some leg fractures lead to dangerous muscle swelling

NCT ID NCT05521958

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study compares genetic differences and muscle gene activity in people who develop acute compartment syndrome after a leg fracture versus those who do not. Researchers will measure a protein called myostatin in muscle tissue. The goal is to better understand why some people get this serious condition, which can lead to muscle damage if not treated quickly.

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Conditions

The condition(s) this trial relates to.

compartment syndrome tibia fracture Tibial Plateau Fractures

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Utah Orthopaedic Center

    Salt Lake City, Utah, 84112, United States