Scientists hunt for genetic clues in lung and esophageal cancers

NCT ID NCT00242723

First seen Jun 25, 2026 · Last updated Jul 31, 2026 · Updated 10 times

Summary

This study aims to collect tumor, normal tissue, and blood samples from up to 1559 people with cancers of the lung, esophagus, or pleura. Researchers will analyze genetic and epigenetic changes to better understand these diseases and identify potential markers for future treatments. Participants undergo standard tests and procedures like bronchoscopy to provide samples, and may be offered enrollment in treatment trials if eligible.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this research could reveal genetic markers that help develop new treatments for thoracic cancers.
What could go wrong
This is an observational study, not a treatment trial. It may not directly benefit participants, and findings may not lead to immediate therapies.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

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Other studies related to the condition(s) this trial covers.