Massive genetic data hunt aims to crack rare disease mysteries

NCT ID NCT05657405

First seen Jun 27, 2026 · Last updated Aug 13, 2026 · Updated 29 times

Summary

This observational study is gathering medical and genetic information from up to 1,250 people with known or suspected genetic conditions, as well as their relatives. Researchers will use advanced data analysis to find new insights into how genes cause disease. Participants may provide blood, saliva, imaging scans, heart tests, and photos. The goal is to develop better tools for analyzing complex genetic data, not to test a treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could lead to better tools for analyzing genetic data, helping doctors understand and diagnose genetic conditions more accurately.
What could go wrong
This is an observational study, not a treatment trial. It may not directly benefit participants, and the tools developed may take years to become available in clinics.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.