Gene therapy vs. cochlear implants: which restores hearing better?

NCT ID NCT06237790

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study compares how well people with a genetic form of deafness (DFNB9) can hear and understand speech after receiving gene therapy versus a cochlear implant. Researchers will also include healthy participants for comparison. The goal is to see if gene therapy can match or outperform cochlear implants, helping doctors create better rehabilitation plans.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

gene therapy

What this could lead to

If successful, this study could show that gene therapy restores hearing as well as or better than cochlear implants, pointing toward a future treatment for certain genetic deafness.

What could go wrong

This is an observational comparison, not a randomized trial, so results may be influenced by differences between groups. Gene therapy is still experimental and may not work for all types of hearing loss.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hearing loss disorder hereditary disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Eye & ENT Hospital of Fudan University

    RECRUITING

    Shanghai, Shanghai Municipality, 200031, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Peking Union Medical College Hospital

    NOT_YET_RECRUITING

    Beijing, Beijing Municipality, 100730, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Nanchang University

    NOT_YET_RECRUITING

    Nanchang, Jiangxi, 330006, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Zhengzhou University

    NOT_YET_RECRUITING

    Zhengzhou, Henan, 450052, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Second Xiangya Hospital of Central South University

    NOT_YET_RECRUITING

    Changsha, Hunan, 410011, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • West China Hospital, Sichuan University

    NOT_YET_RECRUITING

    Chengdu, Sichuan, 610041, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••