Gene therapy tested in toddlers with devastating muscle disease

NCT ID NCT06128564

Summary

This study is testing the safety and biological activity of an experimental gene therapy in very young children with Duchenne muscular dystrophy (DMD). It involves 13 children under 4 years old who will receive a single dose of the therapy and be followed for about 5 years. The main goal is to see if the treatment is safe and if it leads to the production of a needed muscle protein.

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Contacts and locations

Locations

  • Chr de La Citadelle

    Liège, 3500, Belgium

  • Great Ormond Street Hospital for Children

    London, WC1N 3JH, United Kingdom

  • Hospital Sant Joan De Deu

    Esplugues de Llobregas, Barcelona, 08950, Spain

  • Hôpital Necker-Enfants Malades

    Paris, 75015, France

  • John Radcliffe Hospital

    Oxford, OX3 9DU, United Kingdom

  • PU A. Gemelli, Università Cattolica del Sacro Cuore

    Rome, Lazio, 00168, Italy

  • Universitätsklinikum Essen

    Essen, 45147, Germany

Conditions

Explore the condition pages connected to this study.