One shot to save sight? gene therapy aims to replace monthly eye injections

NCT ID NCT05197270

Summary

This trial is testing a one-time gene therapy injection, called 4D-150, for adults with wet age-related macular degeneration (AMD) who currently need regular eye injections to protect their vision. The main goal is to see if this single treatment can safely reduce or eliminate the need for those frequent injections over time. Researchers will follow participants for up to 5 years to check safety and see how long the treatment's effects last.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Austin Clinical Research

    RECRUITING

    Austin, Texas, 78750, United States

    Contact

    Contact Email: •••••@•••••

  • Barnet Delaney Perkins Eye Center

    RECRUITING

    Phoenix, Arizona, 85016, United States

    Contact Email: •••••@•••••

    Contact

  • California Retina Consultants

    RECRUITING

    Oxnard, California, 93036, United States

    Contact Email: •••••@•••••

    Contact

  • Colorado Retina Associates

    RECRUITING

    Lakewood, Colorado, 80288, United States

    Contact Email: •••••@•••••

    Contact

  • Cumberland Valley Retina Consultants

    RECRUITING

    Hagerstown, Maryland, 21740, United States

    Contact

    Contact Email: •••••@•••••

  • Emanuelli Research and Development Center, LLC

    RECRUITING

    Arecibo, Puerto Rico, 00612, Puerto Rico

    Contact

    Contact Email: •••••@•••••

  • Florida Eye Associates

    RECRUITING

    Melbourne, Florida, 32901, United States

    Contact Email: •••••@•••••

    Contact

  • Mid Atlantic Retina

    RECRUITING

    Bethlehem, Pennsylvania, 18017, United States

    Contact

    Contact Email: •••••@•••••

  • Ophthalmic Consultants of Boston & Boston Eye Surgery and Laser Center

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact

    Contact Email: •••••@•••••

  • Pacific Northwest Retina LLC

    WITHDRAWN

    Bellevue, Washington, 98004, United States

  • Palmetto Retina Center, LLC

    RECRUITING

    West Columbia, South Carolina, 29169, United States

    Contact

    Contact Email: •••••@•••••

  • Rand Eye Institute

    SUSPENDED

    Deerfield Beach, Florida, 33064, United States

  • Retina Consultants of Texas

    WITHDRAWN

    The Woodlands, Texas, 77384, United States

  • Retina Partners Midwest

    RECRUITING

    Carmel, Indiana, 46290, United States

    Contact Email: •••••@•••••

    Contact

  • Retina Vitreous Associates of Florida

    RECRUITING

    Tampa, Florida, 33607, United States

    Contact

    Contact Email: •••••@•••••

  • Retina Vitreous Consultants, LLP DBA Retina Group of Florida

    ACTIVE_NOT_RECRUITING

    Fort Lauderdale, Florida, 33308, United States

  • Retinal Consultants Medical Group

    RECRUITING

    Sacramento, California, 95841, United States

    Contact

    Contact Email: •••••@•••••

  • Retinal Specialty Institute

    RECRUITING

    Pensacola, Florida, 32503, United States

    Contact

    Contact Email: •••••@•••••

  • Sierra Eye Associates

    RECRUITING

    Reno, Nevada, 89502, United States

    Contact

    Contact Email: •••••@•••••

  • Tennessee Retina

    RECRUITING

    Nashville, Tennessee, 37203, United States

    Contact

    Contact Email: •••••@•••••

  • University Retina and Macula Associates

    RECRUITING

    Oak Forest, Illinois, 60452, United States

    Contact Email: •••••@•••••

    Contact

  • Valley Retina Institute, PA

    RECRUITING

    McAllen, Texas, 78503, United States

    Contact

    Contact Email: •••••@•••••

  • Verum Research, LLC

    RECRUITING

    Eugene, Oregon, 97401, United States

    Contact

    Contact Email: •••••@•••••

  • Vitreo Retinal Associates

    RECRUITING

    Gainesville, Florida, 32607, United States

    Contact

    Contact Email: •••••@•••••

  • Western Carolina Retinal Associates

    WITHDRAWN

    Asheville, North Carolina, 28803, United States

Conditions

Explore the condition pages connected to this study.