One-Shot gene therapy could free teens from lifelong bleeding disorder treatments

NCT ID NCT07080905

Summary

This study is testing a single-dose gene therapy called CSL222 in teenage boys with severe hemophilia B. The goal is to see if this one-time treatment can help their bodies produce their own clotting factor, reducing or eliminating the need for regular infusions to prevent bleeds. Researchers will measure how often participants bleed, their quality of life, and monitor for any side effects.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Arthur M. Blank Hospital - Children's Healthcare of Atlanta

    RECRUITING

    Atlanta, Georgia, 30329, United States

    Contact

  • Chaim Sheba Medical Center

    RECRUITING

    Ramat Gan, 5262000, Israel

    Contact

  • John Radcliffe Hospital - Oxford University Hospitals NHS

    RECRUITING

    Oxford, OX3 9DU, United Kingdom

    Contact

  • St Thomas Hospital

    RECRUITING

    London, SE1 7EH, United Kingdom

    Contact

  • St. Jude Children's Research Hospital

    RECRUITING

    Memphis, Tennessee, 38105, United States

    Contact

  • University of Florida

    RECRUITING

    Gainesville, Florida, 32611, United States

    Contact

  • University of Michigan Medical Center

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact

Conditions

Explore the condition pages connected to this study.