Doctors test gene fix for 'Bubble Boy' disease in infants

NCT ID NCT01512888

Summary

This study tested a new gene therapy method for infants with SCID-X1, a severe genetic immune disorder. Doctors collected the baby's own bone marrow cells, inserted a corrected gene copy in the lab, and then returned the cells to the baby. The goal was to see if this procedure was safe and could help the baby develop a working immune system, especially for those without a matched sibling donor for a standard transplant.

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Contacts and locations

Locations

  • Seattle Children's Research Institute

    Seattle, Washington, 98101, United States

  • St. Jude Children's Research Hospital

    Memphis, Tennessee, 38105, United States

  • University of California-San Francisco

    San Francisco, California, 94158, United States

Conditions

Explore the condition pages connected to this study.