One-Shot gene therapy tested to halt Parkinson's progression

NCT ID NCT07011771

Summary

This early-stage trial is testing a new, one-time gene therapy called CAP-003 in adults with Parkinson's disease caused by a specific genetic change (GBA1 mutation). The main goals are to see if the treatment is safe and to look for early signs that it might help control the disease. About 31 participants will receive a single infusion and be closely monitored for two years.

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Contacts and locations

Locations

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • Booth Gardner Parkinson's Care Center - Evergreen Neuroscience Institute

    Kirkland, Washington, 98034, United States

  • Inland Northwest Research

    Spokane, Washington, 99202, United States

  • New York Presbyterian Hospital-Columbia University Medical Center

    New York, New York, 10032, United States

  • Rush University Medical Center

    Chicago, Illinois, 60612, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.