One-Shot gene therapy tested for untreatable burning pain

NCT ID NCT06980948

Summary

This early-stage study is testing a new, one-time gene therapy called ST-503 for people with severe, untreatable nerve pain from small fiber neuropathy. The therapy aims to block pain signals at their source by delivering a modified gene directly into the spinal fluid. Researchers will first check if the treatment is safe and then see if it reduces pain levels in the 27 participants.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Columbia University

    NOT_YET_RECRUITING

    New York, New York, 10027, United States

  • Dartmouth Hitchcock Medical Center

    NOT_YET_RECRUITING

    Lebanon, New Hampshire, 03766, United States

  • HonorHealth

    RECRUITING

    Scottsdale, Arizona, 85260, United States

    Contact Email: •••••@•••••

  • Johns Hopkins University

    NOT_YET_RECRUITING

    Baltimore, Maryland, 21218, United States

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Email: •••••@•••••

  • University of Arkansas for Medical Sciences

    NOT_YET_RECRUITING

    Little Rock, Arkansas, 72205, United States

  • University of North Carolina Medical Center

    NOT_YET_RECRUITING

    Chapel Hill, North Carolina, 27514, United States

  • University of Utah

    NOT_YET_RECRUITING

    Salt Lake City, Utah, 84112, United States

  • Vanderbilt University

    NOT_YET_RECRUITING

    Nashville, Tennessee, 37235, United States

  • Virginia Commonwealth University

    NOT_YET_RECRUITING

    Richmond, Virginia, 23284, United States

Conditions

Explore the condition pages connected to this study.