First human test of gene therapy for rare muscle disease

NCT ID NCT05876780

Summary

This early-stage study is testing a single dose of an experimental gene therapy called SRP-9003 in six people with a rare genetic muscle disease called limb girdle muscular dystrophy type 2E/R4. The main goals are to check if the treatment is safe and to see if it increases a needed muscle protein. Researchers will measure changes in muscle strength and movement ability over five years.

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Contacts and locations

Locations

  • Nationwide Children's Hospital

    Columbus, Ohio, 43205, United States

  • St. Jude Children's Research Hospital

    Memphis, Tennessee, 38105, United States

Conditions

Explore the condition pages connected to this study.