One-Shot gene therapy aims to restore sight in genetic blindness trial

NCT ID NCT07406854

Summary

This study is testing a one-time gene therapy injection into the eye to see if it can improve vision in people with a specific genetic form of Leber's hereditary optic neuropathy (LHON), which causes severe vision loss. It will involve about 95 participants, aged 12 to 75, who have had reduced vision for more than 6 months but less than 10 years. The main goal is to see if the treatment is safe and if it leads to meaningful vision improvement compared to a sham (pretend) injection.

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Contacts and locations

Locations

  • Beijing Tongren Hospital, Capital Medical University

    Beijing, Beijing Municipality, China

Conditions

Explore the condition pages connected to this study.