First-Ever gene therapy injected directly into hearts of patients
NCT ID NCT05836259
Summary
This is the first study in people to test a new gene therapy called TN-201 for a genetic heart condition called hypertrophic cardiomyopathy (HCM). It will involve up to 30 adults who have HCM caused by a specific gene mutation (MYBPC3). The main goals are to find a safe dose and see how well the body tolerates a single treatment, which is designed to deliver a working copy of the faulty gene directly to the heart.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Brigham and Women's Hospital
WITHDRAWNBoston, Massachusetts, 02115, United States
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Emory University
WITHDRAWNAtlanta, Georgia, 30322, United States
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Hospital of the University of Pennsylvania
WITHDRAWNPhiladelphia, Pennsylvania, 19104, United States
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Houston Methodist Hospital
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mayo Clinic
RECRUITINGRochester, Minnesota, 55905, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Oregon Health & Science University
WITHDRAWNPortland, Oregon, 97239, United States
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The Christ Hospital Physicians - The Ohio Heart and Vascular Center
WITHDRAWNCincinnati, Ohio, 45219, United States
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UC San Diego Altman Clinical and Translational Research Institute - Center for Clinical Research
RECRUITINGLa Jolla, California, 92093, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of California San Francisco
RECRUITINGSan Francisco, California, 94117, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.