Brain-Delivered gene therapy offers hope for devastating childhood disorder

NCT ID NCT07270549

Summary

This is the first human trial of a gene therapy for children with CTNNB1 syndrome, a severe genetic disorder that affects brain development. Researchers will test if a single dose of a therapy called Urbagen, delivered directly to the brain, is safe and can improve motor function, thinking skills, and quality of life. The study will enroll 12 children aged 2-12 years and follow them for up to five years.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University Medical Centre Ljubljana

    RECRUITING

    Ljubljana, 1000, Slovenia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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Conditions

Explore the condition pages connected to this study.