Spinal injection gene therapy tested for rare nerve disease

NCT ID NCT05394064

Summary

This study tested a one-time gene therapy injection into the spinal fluid for adults with a rare, progressive nerve disease called adrenomyeloneuropathy (AMN). The goal was to see if delivering a working copy of a faulty gene could be safe and potentially slow down the worsening of symptoms, like walking difficulties. The trial was small and ended early, so its full effectiveness is not yet known.

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Contacts and locations

Locations

  • Amsterdam UMC

    Amsterdam, Netherlands

  • University of Massachusetts Chan Medical School

    Worcester, Massachusetts, 01655, United States

Conditions

Explore the condition pages connected to this study.