Experimental gene therapy tested for rare muscle disease

NCT ID NCT06747273

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 23 times

Summary

This early-stage study tested a single dose of SRP-9004 gene therapy in 4 people with limb girdle muscular dystrophy type 2D/R3, a rare muscle-weakening disease. The main goal was to check safety, but researchers also looked at whether the therapy could increase a missing muscle protein. The study was terminated early, so results are limited.

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Contacts and locations

Locations

  • Children's Hospital of the King's Daughters

    Norfolk, Virginia, 23510, United States

  • Nationwide Children's Hospital

    Columbus, Ohio, 43205, United States

Conditions

Explore the condition pages connected to this study.