Bubble boy disease tackled with one-shot gene therapy

NCT ID NCT03217617

First seen Nov 01, 2025 · Last updated Jun 10, 2026 · Updated 32 times

Summary

This trial tests a gene therapy for X-linked severe combined immunodeficiency (SCID-X1), also known as bubble boy disease. It involves a single IV injection of a modified virus to correct the faulty gene. The study aims to restore immune function and reduce infections in 10 patients who lack a suitable bone marrow donor.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Guilin Hospital of Chinese Traditional and Western Medicine

    RECRUITING

    Guilin, Guangxi, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shenzhen Geno-immune Medical Institute

    RECRUITING

    Shenzhen, Guangdong, 518000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.