Light-Activated gene therapy offers new hope for rare blindness

NCT ID NCT03326336

First seen Mar 04, 2026 · Last updated May 16, 2026 · Updated 12 times

Summary

This study tests a new treatment for retinitis pigmentosa, a genetic eye disease that causes vision loss. Ten adults receive a single injection of gene therapy into the eye, then use special glasses that stimulate the treated cells with light. The goal is to see if the treatment is safe and can improve vision.

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Contacts and locations

Locations

  • Centre Hospitalier National d'Ophtalmologie (CHNP) des Quinze-Vingts

    Paris, 75012, France

  • Moorfields Eye Hospital NHS Foundation Trust, 162 City Road

    London, United Kingdom

  • UPMC Eye Center

    Pittsburgh, Pennsylvania, 15213, United States

Conditions

Explore the condition pages connected to this study.