Experimental gene therapy aims to fix rare childhood disease

NCT ID NCT03488394

First seen Jan 11, 2026 · Last updated May 13, 2026 · Updated 17 times

Summary

This study tests a new gene therapy for children with MPS I Hurler, a rare genetic disease that damages organs. The treatment takes the child's own blood stem cells, adds a working copy of the missing gene, and puts them back. The goal is to help the body produce the missing enzyme and control the disease long-term.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Ospedale San Raffaele

    Milan, 20132, Italy

Conditions

Explore the condition pages connected to this study.