First human trial of Gene-Edited lung cells for rare breathing disorder

NCT ID NCT05761899

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new treatment for hereditary pulmonary alveolar proteinosis (hPAP), a rare lung disease where breathing becomes difficult. The therapy involves taking a patient's own lung cells, adding a working gene, and putting them back into the lungs. Only 3 people will join this early-phase trial to check safety and how well the body tolerates the treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hereditary pulmonary alveolar proteinosis pulmonary alveolar proteinosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cincinnati Children's Hospital Medical Center

    RECRUITING

    Cincinnati, Ohio, 45229, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••