First human trial of Gene-Edited lung cells for rare breathing disorder
NCT ID NCT05761899
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new treatment for hereditary pulmonary alveolar proteinosis (hPAP), a rare lung disease where breathing becomes difficult. The therapy involves taking a patient's own lung cells, adding a working gene, and putting them back into the lungs. Only 3 people will join this early-phase trial to check safety and how well the body tolerates the treatment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Cincinnati Children's Hospital Medical Center
RECRUITINGCincinnati, Ohio, 45229, United States