New gene therapy hopes to tame rare metabolic disease in kids

NCT ID NCT06217861

First seen May 16, 2026 · Last updated May 16, 2026

Summary

This early-stage study tests a single-dose gene therapy called VGM-R02b in up to 12 children aged 6 or younger with glutaric acidemia type I, a rare genetic disorder that can cause brain damage. The treatment aims to replace the faulty gene and improve symptoms like movement problems and seizures. The main goals are to check safety and see if the therapy helps control the disease.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Children's Hospital Zhejiang University Shcool of Medicine

    RECRUITING

    Hangzhou, Zhejiang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.