Gene therapy could zap Cocaine's high
NCT ID NCT04884594
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage study tests a gene therapy given through an IV for adults with cocaine use disorder who are in remission. The therapy helps the body produce an enzyme that breaks down cocaine quickly, reducing the drug's pleasurable effects. The main goal is to check safety, with 10 participants being monitored for side effects and enzyme levels.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States